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Microcrystalline Cellulose (MCC)
ZIO
Microcrystalline Cellulose (MCC) is a high-purity, multi-functional food-grade excipient and pharmaceutical excipient derived from natural plant cellulose. It is produced through controlled hydrolysis and purification of α-cellulose, resulting in a white, odorless, tasteless crystalline powder that adheres to global quality benchmarks. As a versatile ingredient, MCC plays pivotal roles across industries: in food, it acts as a stabilizer, thickener, and dietary fiber; in pharmaceuticals, it serves as a tablet diluent, binder, and disintegrant; and it also functions as a carrier in dietary supplements and a thickening agent in cosmetics. Its ability to enhance product stability, texture, and processability makes it an indispensable ingredient for manufacturers.
Beyond food and pharmaceuticals, Microcrystalline Cellulose (MCC) is widely used in dietary supplements to improve formulation consistency and ingredient distribution. In cosmetics, it acts as a suspending agent and absorbent, ideal for skincare and makeup products. Its compatibility with diverse ingredients and compliance with strict standards (including USP, EP, and FCC) ensures it meets the demands of applications ranging from baked goods and dairy products to capsules and oral tablets.
Property | Description |
Chemical Name | Microcrystalline Cellulose |
Molecular Formula | C₆H₁₀O₅ₙ |
Appearance | White to off-white crystalline powder |
Odor | Odorless, tasteless |
Particle Size Range | 20μm – 200μm (customizable grades: MCC101, MCC102, etc.) |
Solubility | Insoluble in water and organic solvents, but dispersible |
Density | Approx. 1.5 g/cm³ |
Safety | Complies with USP, EP, FCC standards; safe and stable raw material |
Functional Properties | Excellent compressibility and binding ability |
Superior dispersibility and stability | |
Low hygroscopicity for easy storage | |
Good suspension and emulsification properties |
The sole active ingredient in Microcrystalline Cellulose (MCC) is high-purity α-cellulose, extracted from natural plant sources (such as wood or cotton). This raw material undergoes rigorous hydrolysis to remove non-cellulosic impurities, followed by purification to achieve the desired crystalline structure. The absence of synthetic additives, preservatives, or harmful substances ensures MCC maintains its natural origin and safety profile, making it suitable for consumption in food and pharmaceutical products.
Every batch of Microcrystalline Cellulose (MCC) is tested to meet USP standards, EP standards, and FCC standards—ensuring consistency in purity, particle size, and functional properties. This strict quality control guarantees reliable performance, whether MCC is used as a food stabilizer, pharmaceutical binder, or supplement carrier.
In pharmaceutical applications, Microcrystalline Cellulose (MCC) offers excellent compressibility, enabling the production of hard, uniform tablets with consistent hardness and dissolution rates. Its superior dispersibility ensures even distribution of active pharmaceutical ingredients (APIs), while its role as a disintegrant promotes rapid tablet breakdown in the body—enhancing API absorption. Additionally, its low hygroscopicity prevents moisture absorption during storage, preserving the stability of sensitive pharmaceutical products (such as moisture-sensitive tablets).
As a food ingredient, Microcrystalline Cellulose (MCC) acts as a food stabilizer to prevent ingredient separation in products like ice cream and beverages, and as a food thickener to improve texture in sauces and dairy items. As a dietary fiber, it supports digestive health without adding excess calories, making it ideal for low-sugar, weight-management, and diabetic-friendly foods. In dietary supplements, it serves as a neutral carrier, ensuring active ingredients are evenly dispersed and easy to formulate into powders or capsules.
Microcrystalline Cellulose (MCC) requires moisture-proof storage—store in a cool, dry place in sealed containers to avoid clumping, as excessive moisture can reduce its flowability and functional performance. Keep it away from direct sunlight and heat sources to maintain its crystalline structure and purity, which are critical for its effectiveness in formulations.
When formulating with Microcrystalline Cellulose (MCC), follow industry best practices and comply with regional USP standards, EP standards, or FCC standards. For pharmaceutical use, consult a formulation specialist to select the appropriate MCC grade (e.g., MCC 101, MCC 102) — different grades offer varying particle sizes and compressibility, tailored to specific product needs (such as tablet hardness or supplement texture).
Yes, Microcrystalline Cellulose (MCC) is globally recognized as safe for food and pharmaceutical use. It complies with USP standards, EP standards, and FCC standards, and is approved by regulatory bodies worldwide for inclusion in consumable products.
Absolutely. Derived from natural plant cellulose, Microcrystalline Cellulose (MCC) is officially classified as a dietary fiber and can be added to food or supplements to support digestive health and meet daily fiber requirements.
A3: No, Microcrystalline Cellulose (MCC) is insoluble in water but exhibits excellent dispersibility. When mixed with liquids, it forms a stable suspension—making it effective as a stabilizer and thickener in aqueous food and pharmaceutical products.
Microcrystalline Cellulose (MCC) is a high-purity, multi-functional food-grade excipient and pharmaceutical excipient derived from natural plant cellulose. It is produced through controlled hydrolysis and purification of α-cellulose, resulting in a white, odorless, tasteless crystalline powder that adheres to global quality benchmarks. As a versatile ingredient, MCC plays pivotal roles across industries: in food, it acts as a stabilizer, thickener, and dietary fiber; in pharmaceuticals, it serves as a tablet diluent, binder, and disintegrant; and it also functions as a carrier in dietary supplements and a thickening agent in cosmetics. Its ability to enhance product stability, texture, and processability makes it an indispensable ingredient for manufacturers.
Beyond food and pharmaceuticals, Microcrystalline Cellulose (MCC) is widely used in dietary supplements to improve formulation consistency and ingredient distribution. In cosmetics, it acts as a suspending agent and absorbent, ideal for skincare and makeup products. Its compatibility with diverse ingredients and compliance with strict standards (including USP, EP, and FCC) ensures it meets the demands of applications ranging from baked goods and dairy products to capsules and oral tablets.
Property | Description |
Chemical Name | Microcrystalline Cellulose |
Molecular Formula | C₆H₁₀O₅ₙ |
Appearance | White to off-white crystalline powder |
Odor | Odorless, tasteless |
Particle Size Range | 20μm – 200μm (customizable grades: MCC101, MCC102, etc.) |
Solubility | Insoluble in water and organic solvents, but dispersible |
Density | Approx. 1.5 g/cm³ |
Safety | Complies with USP, EP, FCC standards; safe and stable raw material |
Functional Properties | Excellent compressibility and binding ability |
Superior dispersibility and stability | |
Low hygroscopicity for easy storage | |
Good suspension and emulsification properties |
The sole active ingredient in Microcrystalline Cellulose (MCC) is high-purity α-cellulose, extracted from natural plant sources (such as wood or cotton). This raw material undergoes rigorous hydrolysis to remove non-cellulosic impurities, followed by purification to achieve the desired crystalline structure. The absence of synthetic additives, preservatives, or harmful substances ensures MCC maintains its natural origin and safety profile, making it suitable for consumption in food and pharmaceutical products.
Every batch of Microcrystalline Cellulose (MCC) is tested to meet USP standards, EP standards, and FCC standards—ensuring consistency in purity, particle size, and functional properties. This strict quality control guarantees reliable performance, whether MCC is used as a food stabilizer, pharmaceutical binder, or supplement carrier.
In pharmaceutical applications, Microcrystalline Cellulose (MCC) offers excellent compressibility, enabling the production of hard, uniform tablets with consistent hardness and dissolution rates. Its superior dispersibility ensures even distribution of active pharmaceutical ingredients (APIs), while its role as a disintegrant promotes rapid tablet breakdown in the body—enhancing API absorption. Additionally, its low hygroscopicity prevents moisture absorption during storage, preserving the stability of sensitive pharmaceutical products (such as moisture-sensitive tablets).
As a food ingredient, Microcrystalline Cellulose (MCC) acts as a food stabilizer to prevent ingredient separation in products like ice cream and beverages, and as a food thickener to improve texture in sauces and dairy items. As a dietary fiber, it supports digestive health without adding excess calories, making it ideal for low-sugar, weight-management, and diabetic-friendly foods. In dietary supplements, it serves as a neutral carrier, ensuring active ingredients are evenly dispersed and easy to formulate into powders or capsules.
Microcrystalline Cellulose (MCC) requires moisture-proof storage—store in a cool, dry place in sealed containers to avoid clumping, as excessive moisture can reduce its flowability and functional performance. Keep it away from direct sunlight and heat sources to maintain its crystalline structure and purity, which are critical for its effectiveness in formulations.
When formulating with Microcrystalline Cellulose (MCC), follow industry best practices and comply with regional USP standards, EP standards, or FCC standards. For pharmaceutical use, consult a formulation specialist to select the appropriate MCC grade (e.g., MCC 101, MCC 102) — different grades offer varying particle sizes and compressibility, tailored to specific product needs (such as tablet hardness or supplement texture).
Yes, Microcrystalline Cellulose (MCC) is globally recognized as safe for food and pharmaceutical use. It complies with USP standards, EP standards, and FCC standards, and is approved by regulatory bodies worldwide for inclusion in consumable products.
Absolutely. Derived from natural plant cellulose, Microcrystalline Cellulose (MCC) is officially classified as a dietary fiber and can be added to food or supplements to support digestive health and meet daily fiber requirements.
A3: No, Microcrystalline Cellulose (MCC) is insoluble in water but exhibits excellent dispersibility. When mixed with liquids, it forms a stable suspension—making it effective as a stabilizer and thickener in aqueous food and pharmaceutical products.
